Table 3.
Mean of Ten SLF and Motor Tracts Specific Measurements of Diffusion Indices and Statistical Analysis Between Healthy Cannabis Users and Normal Controls.
| Fiber Bundle | Healthy Controls (n=14) | Heavy Cannabis Users (n=14) | Test Statistic* | P |
|---|---|---|---|---|
| Diffusion Measures 10 Measurements (Arbitrary Units) |
Mean (SD)** | Mean (SD)** | ||
| Left SLF | ||||
| Fractional Anisotropy (FA) | 311.07 (15.97) | 294.73 (17.89) | 2.774 | .11 |
| Radial Diffusivity (λ⊥) | 788.58 (68.64) | 843.73 (54.22) | 5.92 | .02 |
| Axial Diffusivity (λ11) | 1376.79 (38.25) | 1351.98 (36.91) | 0.727 | .40 |
| Trace (Dtr) | 2956.53 (145.43) | 3042.27 (103.06) | 4.655 | .04 |
| Right SLF | ||||
| Fractional Anisotropy (FA) | 306.83 (12.73) | 292.57 (14.13) | 6.151 | .02 |
| Radial Diffusivity (λ⊥) | 774.09 (73.20) | 832.56 (53.82) | 7.331 | .01 |
| Axial Diffusivity (λ11) | 1356.74 (34.31) | 1331.24 (42.96) | 1.174 | .29 |
| Trace (Dtr) | 2904.98 (156.86) | 2997.69(114.90) | 5.162 | .03 |
| Left Motor | ||||
| Fractional Anisotropy (FA) | 377.81 (20.07) | 371.52 (19.88) | 1.293 | .27 |
| Radial Diffusivity (λ⊥) | 744.49 (98.12) | 717.14 (38.55) | .001 | .97 |
| Axial Diffusivity (λ11) | 1461.65 (118.26) | 1340.71 (66.25) | 7.739 | .01 |
| Trace (Dtr) | 2950.69 (281.76) | 2774.40 (93.25) | 1.777 | .20 |
| Right Motor | ||||
| Fractional Anisotropy (FA) | 367.41 (18.01) | 359.90 (19.88) | 1.146 | .30 |
| Radial Diffusivity (λ⊥) | 736.37 (79.90) | 722.86 (57.12) | .189 | .67 |
| Axial Diffusivity (λ11) | 1425.58 (110.27) | 1319.32 (65.19) | 6.519 | .02 |
| Trace (Dtr) | 2898.37 (242.93) | 2761.29 (139.12) | .948 | .34 |
*
All analyses were performed using analysis of covariance, controlling for WRAT3 (Wilkinson 1993) Reading scores.
**
All diffusion parameters were multiple by 1000.