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. Author manuscript; available in PMC: 2012 Mar 28.
Published in final edited form as: Future Virol. 2010 Jan;5(1):65–83. doi: 10.2217/fvl.09.69

Figure 3. Human herpesvirus lytic origins of replication.

Figure 3

Inverted repeats containing binding sites for known origin-binding proteins are noted with red boxes. AT-rich regions are boxed in blue and Y-block elements are boxed in green. Flanking divergent genes are shown in yellow. Essential elements have also been noted.

CMV: Cytomegalovirus; DEE: Downstream essential element; EBV: Epstein–Barr virus; EE1: Essential element 1; EE2: Essential element 2; KSHV: Kaposi’s sarcoma-associated herpesvirus; HSV: Herpes simplex virus; IE2RE: Immediate-early gene 2 response element; OriLyt: Origin of lytic replication; OriS: Repeated short-region origin of replication; REE: Rta response element; SRT: Cytomegalovirus OriLyt transcript; UEE: Upstream essential element; ZRE: Zta response element.