Table 2.

Summary of immunohistochemical observations

	Tau-nY18	Tau-nY29	Tau-nY197	Tau-nY394	Tau-Y197
CBD
Neuropil threads	±	+	+	−	+
Coiled bodies	−	+	−	−	+
Perinuclear inclusions	−	+	−	−	+
Globose tangles	−	+	−	−	+
Astrocytic plaques	−	−	−	−	+
PSP
Globose tangles	−	+	−	−	+
Neuropil threads	−	+	+	−	+
Perinuclear inclusions	−	+	−	−	+
Coiled bodies	−	+	±	−	+
Thorny and tufted astrocytes	−	+	−	−	+
PiD
Pick bodies	±	+	+	−	+
Coiled bodies	−	±	−	−	+
Neuropil threads	−	+	+	−	+

Immunohistochemistry (IHC) was performed on tissue sections from corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and Pick’s disease (PiD) using site-specific nitro-tau antibodies and the qualitative observations are presented above

+, pathology observed; −, pathology not observed; ±, limited pathology observed