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. 2012 Mar 12;122(4):1377–1392. doi: 10.1172/JCI58642

Figure 1. Structure of new high-affinity Aβ/RAGE blockers.

Figure 1

FPS1, FPS2, and FPS3 derived from the primary screen. FPS-ZM1 derived from the secondary screen. Each structure shows the tertiary amide group (red) and its functional moieties, hydrophobic group (blue), electron-rich aromatic group (green), and electron-poor group (pink). For details see Results.