Figure 6. H. pylori expressing phosphomimetic CagA mutants induce AGS cell elongation during infection.

(A) AGS cells were infected for 4 hours with CagA-expressing H. pylori strains as indicated. The number of elongated cells in each experiment was quantitated in triplicate in 10 different 0.25-mm² fields. (B) Representative phase-contrast micrographs of infected AGS cells as indicated. *P ≤ 0.01; **P ≤ 0.001.