Table 1.
Treatment | Time (d) to reach 4 times the treatment volume (mean ± SEM) | Evidence of local invasion or lymph node metastases | No. of lung metastases (mean ± SEM) |
Control diet, no radiation | 12.7 ± 0.8 | none | 29.7 ± 7.2d |
Fenbendazole diet, no radiation | 12.1 ± 0.6a | none | 29.7 ± 4.3d |
Control diet, tumor irradiation | 17.5 ± 1.3b | none | 28.6 ± 3.9d |
Fenbendazole diet, tumor irradiation | 20.4 ± 0.9bc | none | 24.3 ± 9.1d |
The significance of differences between groups was assessed by using Mann–Whitney U tests.
Not significantly different (P = 0.32) from value for tumors in unirradiated mice on the control diet.
Significantly different (P < 0.05) from value for unirradiated tumors.
Not significantly different (P = 0.12) from value for tumors in irradiated mice on the control diet.
None of the differences between groups were statistically significant (P > 0.05 for all comparisons).