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. Author manuscript; available in PMC: 2013 Mar 7.
Published in final edited form as: J Med Chem. 2012 Feb 28;55(5):1940–1956. doi: 10.1021/jm201006x

Figure 2.

Figure 2

Comparison of the effects of MOMIPP (compound 19) and MIPP (compound 2) on growth and viability of U251 GBM cells. (A). One day after plating the cells in 96 well dishes MOMIPP (●) or MIPP (■) was added at the indicated concentrations. Controls consisted of cells in parallel wells treated with an equivalent volume of vehicle (DMSO). Medium containing fresh compound was added after 24 h and MTT assays were performed after a total 48 h treatment. Each point represents the mean (± S.D.) from four separate wells, with the results expressed as percent of the mean of the parallel control wells. (B) U251 cells seeded in parallel 35 mm dishes were treated with MOMIPP (●), MIPP (■) or an equivalent volume of DMSO (▲) and cells were harvested for counting on each of three consecutive days. Each point is a mean ± S.D. from three separate cultures.