Skip to main content
. Author manuscript; available in PMC: 2013 Mar 7.
Published in final edited form as: J Med Chem. 2012 Feb 28;55(5):1940–1956. doi: 10.1021/jm201006x

Figure 4.

Figure 4

Comparison of the abilities of MOMIPP and MIPP to inhibit survival of U251 GBM cells in colony-forming assays. (A) Cells were plated for colony-forming assays as described in the Experimental Section. One day after plating the cells, MOMIPP (●) or MIPP (■) was added to the medium at the indicated concentrations and cells were maintained in the presence of the compounds for 48 h. Thereafter the compounds were removed and colonies >50 cells were counted after two weeks. Each point represents the mean (± S.D.) from three separate dishes, with the results expressed as percent of the mean of the parallel control dishes containing DMSO. (B) The effects MOMIPP (●) and MIPP (■) on colony formation were compared as in panel A, except that cells were exposed to the compounds for only 4 h instead of 48 h.