Skip to main content
. Author manuscript; available in PMC: 2013 Mar 7.
Published in final edited form as: J Med Chem. 2012 Feb 28;55(5):1940–1956. doi: 10.1021/jm201006x

Figure 6.

Figure 6

Comparison of the effects of MOMIPP (compound 19), 5-azido-MIPP (compound 36) and 6-azido-MOMIPP (compound 41) on morphology and viability of U251 glioblastoma cells. (A) The indicated compounds were added to the cells at concentrations of 2.5 μM or 10 μM and the cells were observed by phase-contrast microscopy after 48 h. (B & C) U251 cells were treated with varying concentrations of the indicated compounds for 48 h and long term cell viability was assessed by colony-forming assays. Each represents the counts from three dishes (mean ±S.D.), with the results expressed as percent of the mean from parallel control dishes treated with an equivalent volume of vehicle alone (DMSO).