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. 2012 Mar 28;7(3):e34366. doi: 10.1371/journal.pone.0034366

Table 2. List of HPV-16 positive patients together with their major clinical, virological and pathological determinants.

ID Age DNAviral load RCA Cytology Kolposcopy Histology Stage (FIGO) Hist Grade LymphNode Met DistantMet
Z A 51 3,17×10−3 ND Normal ND Negative - - - -
E L 44 3,00×10−4 ND Normal ND Negative - -
V M 32 2,19×10−2 ND Normal ND Negative - - - -
Q M 50 3,50×10−2 Positive Normal ND Negative - - - -
H C 55 1,98×10−3 ND Normal ND Negative - - - -
H S 51 2,30×10−3 ND Normal ND Negative - - - -
B Z 51 3,11×10−3 ND Normal ND Negative - - - -
D H 48 1,52×10−2 ND HSIL ANTZ G1 CIN-II - - - -
E M 35 7,60×10−3 ND HSIL ANTZ G2 CIN-III - - - -
M B 40 3,30×10−3 ND HSIL ANTZ G2 CIN-III - - - -
M T 31 9,2×10−3 ND HSIL ANTZ G2 CIN-II - - - -
L B 43 6,68×10−2 ND HSIL ANTZ G1 CIN-III - - - -
T S 39 4,27×10−3 ND HSIL ANTZ G2 CIN-III - - - -
M R 55 1,1×102 Positive HSIL/worse ANTZ G2 Invasive SCC IIA G3 No No
D A 48 5,60×101 Positive HSIL/worse ANTZ G2 Invasive SCC IIB G3 No No
M S 64 2,00×101 ND HSIL/worse ANTZ G1 Invasive SCC IB1 G2 No No
C G 44 1,81×101 ND HSIL/worse ANTZ G2 Invasive SCC IIB G3 No No
D′A A 68 9,20×10−4 ND HSIL/worse ANTZ G1 Invasive SCC, with basaloid aspects IIA G2 No No
G I 40 5,88×100 ND HSIL/worse ANTZ G2 Invasive EC IIB G3 No No
N B 59 3,00×102 ND HSIL/worse ANTZ G2 Invasive SCC, IIB G3 No No
F R 52 6,23×10−1 ND HSIL/worse ANTZ G2 Invasive EC IIB G3 Yes No
S C 47 2,35×102 ND HSIL/worse ANTZ G2 Invasive SCC, IIB G3 No No
A M 43 1,22×101 ND HSIL/worse ANTZ G2 Invasive SCC, IA1 G3 No No
P B 45 3,00×100 ND HSIL/worse ANTZ G2 Invasive SCC, IIA G2 No No
C C 46 4,60×102 ND HSIL/worse ANTZ G2 Invasive SCC, IIA G3 No No
A M 52 6,50×102 ND HSIL/worse ANTZ G2 Invasive SCC, IIB G2 No No
P MC 55 5,4×101 ND HSIL/worse ANTZ G2 Invasive SCC, IIA G3 No No
G.R 73 3,60×10−3 ND HSIL/worse ANTZ G2 Invasive EC IIA G2 Yes No
A.LE 70 7,80×100 ND HSIL/worse ANTZ G2 Invasive SCC, IB2 G3 No No
M P 58 1,25×103 ND HSIL/worse ANTZ G2 Invasive SCC IB2 G2 No No
M M 75 7,30×10−2 ND HSIL/worse ANTZ G1 Invasive SCC, IB2 G2 No No
P E 53 1,7×100 ND HSIL/worse ANTZ G2 Invasive SCC, IIB G3 No No
M M 56 7,43×102 ND HSIL/worse ANTZ G2 Invasive EC IB2 G2 No No
V A 49 4,91×10−2 ND HSIL/worse ANTZ G2 Invasive SCC, IIA G3 Yes No
M GM 51 6,90×101 ND HSIL/worse ANTZ G2 Invasive SCC, IIB G2 Yes No
D′A L 47 1,3×10−1 ND HSIL/worse ANTZ G2 Invasive SCC, IIA G3 No No
T E 59 8,3×102 ND HSIL/worse ANTZ G2 Invasive SCC, IA2 G3 No No
M R 56 7,70×100 ND HSIL/worse ANTZ G2 Invasive SCC, IB1 G2 No No
HK-168 - 2.8×100 ND ND - HPV-16 in vitro transformed human keratinocytes - - - -
SiHa - 1.09×100 ND ND - Invasive SCC cell line - - - -
Caski - 655×102 ND ND - Invasive SCC cell line - - - -
HaCaT - ND ND ND - Spontaneously Immortalized human keratinocytes cell line - - - -

ID: patient's identification code; DNA viral load was calculated as the E6/beta globin ratio and expressed in copy per haploid cellular genome CHCG; HSIL: High grade Squamous Intraepithelial Lesion; ANTZ: Abnormal Transformation Zone; Histological Grade: G1 Well differentiated; G2 Moderately differentiated; G3 Poorly differentiated. Met: metastases. ND: none detected; SCC samples selected for redox-proteomics analysis are boxed.