Table 2. List of HPV-16 positive patients together with their major clinical, virological and pathological determinants.
ID | Age | DNAviral load | RCA | Cytology | Kolposcopy | Histology | Stage (FIGO) | Hist Grade | LymphNode Met | DistantMet |
Z A | 51 | 3,17×10−3 | ND | Normal | ND | Negative | - | - | - | - |
E L | 44 | 3,00×10−4 | ND | Normal | ND | Negative | - | – | – | - |
V M | 32 | 2,19×10−2 | ND | Normal | ND | Negative | - | - | - | - |
Q M | 50 | 3,50×10−2 | Positive | Normal | ND | Negative | - | - | - | - |
H C | 55 | 1,98×10−3 | ND | Normal | ND | Negative | - | - | - | - |
H S | 51 | 2,30×10−3 | ND | Normal | ND | Negative | - | - | - | - |
B Z | 51 | 3,11×10−3 | ND | Normal | ND | Negative | - | - | - | - |
D H | 48 | 1,52×10−2 | ND | HSIL | ANTZ G1 | CIN-II | - | - | - | - |
E M | 35 | 7,60×10−3 | ND | HSIL | ANTZ G2 | CIN-III | - | - | - | - |
M B | 40 | 3,30×10−3 | ND | HSIL | ANTZ G2 | CIN-III | - | - | - | - |
M T | 31 | 9,2×10−3 | ND | HSIL | ANTZ G2 | CIN-II | - | - | - | - |
L B | 43 | 6,68×10−2 | ND | HSIL | ANTZ G1 | CIN-III | - | - | - | - |
T S | 39 | 4,27×10−3 | ND | HSIL | ANTZ G2 | CIN-III | - | - | - | - |
M R | 55 | 1,1×102 | Positive | HSIL/worse | ANTZ G2 | Invasive SCC | IIA | G3 | No | No |
D A | 48 | 5,60×101 | Positive | HSIL/worse | ANTZ G2 | Invasive SCC | IIB | G3 | No | No |
M S | 64 | 2,00×101 | ND | HSIL/worse | ANTZ G1 | Invasive SCC | IB1 | G2 | No | No |
C G | 44 | 1,81×101 | ND | HSIL/worse | ANTZ G2 | Invasive SCC | IIB | G3 | No | No |
D′A A | 68 | 9,20×10−4 | ND | HSIL/worse | ANTZ G1 | Invasive SCC, with basaloid aspects | IIA | G2 | No | No |
G I | 40 | 5,88×100 | ND | HSIL/worse | ANTZ G2 | Invasive EC | IIB | G3 | No | No |
N B | 59 | 3,00×102 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIB | G3 | No | No |
F R | 52 | 6,23×10−1 | ND | HSIL/worse | ANTZ G2 | Invasive EC | IIB | G3 | Yes | No |
S C | 47 | 2,35×102 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIB | G3 | No | No |
A M | 43 | 1,22×101 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IA1 | G3 | No | No |
P B | 45 | 3,00×100 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIA | G2 | No | No |
C C | 46 | 4,60×102 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIA | G3 | No | No |
A M | 52 | 6,50×102 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIB | G2 | No | No |
P MC | 55 | 5,4×101 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIA | G3 | No | No |
G.R | 73 | 3,60×10−3 | ND | HSIL/worse | ANTZ G2 | Invasive EC | IIA | G2 | Yes | No |
A.LE | 70 | 7,80×100 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IB2 | G3 | No | No |
M P | 58 | 1,25×103 | ND | HSIL/worse | ANTZ G2 | Invasive SCC | IB2 | G2 | No | No |
M M | 75 | 7,30×10−2 | ND | HSIL/worse | ANTZ G1 | Invasive SCC, | IB2 | G2 | No | No |
P E | 53 | 1,7×100 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIB | G3 | No | No |
M M | 56 | 7,43×102 | ND | HSIL/worse | ANTZ G2 | Invasive EC | IB2 | G2 | No | No |
V A | 49 | 4,91×10−2 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIA | G3 | Yes | No |
M GM | 51 | 6,90×101 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIB | G2 | Yes | No |
D′A L | 47 | 1,3×10−1 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IIA | G3 | No | No |
T E | 59 | 8,3×102 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IA2 | G3 | No | No |
M R | 56 | 7,70×100 | ND | HSIL/worse | ANTZ G2 | Invasive SCC, | IB1 | G2 | No | No |
HK-168 | - | 2.8×100 | ND | ND | - | HPV-16 in vitro transformed human keratinocytes | - | - | - | - |
SiHa | - | 1.09×100 | ND | ND | - | Invasive SCC cell line | - | - | - | - |
Caski | - | 655×102 | ND | ND | - | Invasive SCC cell line | - | - | - | - |
HaCaT | - | ND | ND | ND | - | Spontaneously Immortalized human keratinocytes cell line | - | - | - | - |
ID: patient's identification code; DNA viral load was calculated as the E6/beta globin ratio and expressed in copy per haploid cellular genome CHCG; HSIL: High grade Squamous Intraepithelial Lesion; ANTZ: Abnormal Transformation Zone; Histological Grade: G1 Well differentiated; G2 Moderately differentiated; G3 Poorly differentiated. Met: metastases. ND: none detected; SCC samples selected for redox-proteomics analysis are boxed.