Skip to main content
. 2012 Mar 28;7(3):e34378. doi: 10.1371/journal.pone.0034378

Table 1. Parameters for lipid related products in liver and plasma.

Wt-tp mice Cd36−/−-tp mice Msr1 −/−-tp mice
Liver
Triglycerides (µg) 0.38 (±0.02) 0.40 (±0.03) 0.47 (±0.02)*
Free fatty acids (µg) 0.17 (±0.003) 0.19 (±0.006) 0.20 (±0.01)*
Cholesterol (µg) 0.08 (±0.0038) 0.10 (±0.0062) 0.11 (±0.0071)**
Lathosterol (ng/mg liver) 21.8 (±1.76) 19.71 (±2.44) 19.10 (±2.55)
Desmosterol (ng/mg liver) 16.11 (±1.06) 14.44 (±0.85) 12.62 (±0.92)*
Cholestanol (ng/mg liver) 93.03 (±8.42) 97.33 (±6.38) 126.7 (±11.22)*, #
Cholesterol esters (µg/mg liver) 14.37 (±1.58) 21.2 (±1.88)* 20.99 (±1.27)**
Free cholesterol (µg/mg liver) 8.63 (±0.28) 9.00 (±0.23) 8.16 (±0.36)
Plasma
Triglycerides (mM) 1.49 (±0.16) 1.29 (±0.14) 1.27 (±0.18)
Free fatty acids (mM) 0.58 (±0.04) 0.59 (±0.06) 0.45 (±0.03)
Cholesterol (mg/dl) 1052 (±113.1) 1210 (±37.76) 1097 (±69.45)
Lathosterol (mg/dl) 0.31 (±0.03) 0.24 (±0.04) 0.17 (±0.03)**
Desmosterol (mg/dl) 0.77 (±0.06) 0.77 (±0.08) 0.52 (±0.06)*, #
Cholestanol (mg/dl) 3.03 (±0.31) 4.34 (±0.13)** 4.60 (±0.14)**
7α-OH cholesterol (ng/ml) 1.50 (±0.13) 1.02 (±0.13)* 0.92 (±0.03)**
24-OH cholesterol (ng/ml) 448.8 (±46.85) 506.5 (±28.77) 505.6 (±41.62)
27-OH cholesterol (ng/ml) 504 (±59.81) 504.8 (±42.63) 455 (±46.12)
MDA-LDL IgM (RLU) 86348 (±4857) 89405 (±6189) 113896 (±2889)***,##
CuOx-LDL IgM (RLU) 31987 (±6331) 62903 (±11844)* 102371 (±6341)***,##
T15id+ (IgM) (RLU) 3726 (±395.2) 9000 (±1815)* 19079 (±3412)**, #
ALT (U/l) 61 (±9.35) 58.43 (±3.40) 65.5 (±3.53)
AST (U/l) 129.5 (±13.77) 79 (±14.3)* 84 (±6.52)*
AST/ALT 2.25 (±0.38) 1.52 (±0.15) 1.28 (±0.07)*
*

Significantly different from Wt-tp group. *, ** and *** indicate p<0.05, 0.01 and 0.001, respectively. RLU: Relative light unit.

#

Significantly difference between Cd36−/−-tp and Msr1−/−-tp mice. # and ## indicate p<0.05 and 0.01 respectively.