Figure 2. Structural alignment of KLC1-TPR with p67phox and HOP1.

(A) KLC1-TPR (orange) is aligned with the p67phox TPR domain (marine) in complex with Rac1 (Yellow). (B) KLC1-TPR (orange) is aligned with the HOP1 TPR domain (marine) in complex with Hsc70 peptide (Yellow). Residues lining the interaction interface of the p67phox and HOP1 TPR domains and their respective binding partners as well as the corresponding KLC1-TPR residues are shown in the circle.