Table 2. Secondary structure alignments with other known TPR domains.

		KLC1-TPR	KLC2-TPR
HOP1 TPR1A	Z-Score	9.8	11.5
(PDB: 1ELW)	Aligned Residuesa	117	114
	RMSDb	2.1 Å	2.8 Å
	TPR Repeatsc	2–4	2–4
PP5	Z-Score	10.5	11.9
(PDB: 1A17)	Aligned Residuesa	124	109
	RMSDb	2.8 Å	3.0 Å
	TPR Repeatsc	3–5	2–4
PEX5P	Z-Score	13.1	13.6
(PDB: 2J9Q)	Aligned Residuesa	157	157
	RMSDb	3.2 Å	2.8 Å
	TPR Repeatsc	2–6	2–6
SGT	Z-Score	10.3	11.4
(PDB: 2VYI)	Aligned Residuesa	123	123
	RMSDb	2.6 Å	3.0 Å
	TPR Repeatsc	2–4	2–4
Consensus	Z-Score	12.7	13.4
(PDB: 2FO7)	Aligned Residuesa	126	123
	RMSDb	2.1 Å	2.8 Å
	TPR Repeatsc	3–6	1–4
P67phox	Z-Score	13	12.5
(PDB: 1WM5)	Aligned Residuesa	157	157
	RMSDb	2.6 Å	2.9 Å
	TPR Repeatsc	1–4	2–5

^aAligned Residues: Number of aligned residues.

^bRMSD: Root mean square deviation.

^cTPR Repeats: TPR repeats of KLCs that were aligned.