Table 7. Pooled analysis: ALS outcome association with genes implicated by previous GWA studies.

				Pooled analysis (without WTCCC2 controls)		Pooled analysis (with WTCCC2 controls)
Chr	SNP	pos (build 36)	Gene	OR (95% CI)	P	OR (95% CI)	p
9	rs3849942*	27543281	9p21.2	1.1 (0.9, 1.3)	0.17	1.1 (0.9, 1.2)	0.46
7	rs17174381	153709165	DPP6	2.1 (1.3, 3.5)	0.0051	1.9 (1.3, 2.8)	4.4E-04
7	rs10260404*	153841731	DPP6	1.1 (0.9, 1.2)	0.47	1.0 (0.9, 1.1)	0.97
8	rs6985069	28142007	ELP3	0.7 (0.6, 0.9)	2.7E-04	0.8 (0.7, 0.9)	4.8E-04
8	rs13268953*	28111155	ELP3	1.0 (0.8, 1.1)	0.83	1.0 (0.9, 1.1)	0.97
12	rs11048556	26559935	ITPR2	1.3 (0.9, 1.7)	0.14	1.4 (1.1, 1.9)	0.0068
12	rs2306677*	26527653	ITPR2	1.0 (0.7, 1.3)	0.84	0.9 (0.7, 1.1)	0.25
19	rs3746200	17573374	UNC13A	0.8 (0.6, 1.0)	0.050	0.7 (0.6, 0.9)	0.0068
19	rs12608932* +	17613689	UNC13A	1.2 (1.0, 1.5)	0.039	1.2 (1.0, 1.4)	0.046

*Associated SNPs from previous GWAS.

⁺Results from discovery phase only (SNP failed in replication).