Skip to main content
. 2012 Mar 28;7(3):e34062. doi: 10.1371/journal.pone.0034062

Figure 1. CpG-B, not CpG-A, treatment induces mortality in otherwise sublethal rickettsial infection.

Figure 1

B6 mice (8 mice per group) were injected i.v. with different doses of R. australis (Ra) (A). At day 2 after infection with 5×105 pfu of R. australis, 50 µg of ODN control (ODN 1826 control) and CpG-B (ODN 1826) per mouse were injected i.v., respectively (B). At day 2 after B6 mice (8 mice per group) were injected i.v. with R. australis (6×105 pfu), 50 µg of ODN control (ODN 1585 control), CpG-A (ODN 1585), and CpG-B (ODN 1826) per mouse were injected i.v., respectively (C). Survival was monitored for 14 days.