Table 1. Demographic characteristics for Merkel cell carcinoma (MCC) patients provided for the overall cohort as well as by group for histology/MCV viral status.
| Total, n (%) | Histology negative/MCV negative | Histology negative/MCV positive | Histology positive/MCV negative | Histology positive/MCV positive | P-value | |
|---|---|---|---|---|---|---|
| Number of patients (n) | 25 | 12 | 8 | 2 | 3 | |
| Age, median in years | 61 | 67 | 57 | 56 | 68 | 0.13 |
| Sex | ||||||
| Male | 16 (64%) | 9 | 6 | 1 | 0 | 0.07 |
| Female | 9 (36%) | 3 | 2 | 1 | 3 | |
| Location | ||||||
| Upper extremity | 10 (40%) | 4 | 4 | 0 | 2 | 0.82 |
| Head | 8 (32%) | 3 | 3 | 1 | 1 | |
| Lower extremity | 6 (24%) | 4 | 1 | 1 | 0 | |
| Trunk | 1 (4%) | 1 | 0 | 0 | 0 | |
| T-stage | ||||||
| 1 | 11 (44%) | 4 | 4 | 2 | 1 | 0.7 |
| 2 | 2 (8%) | 1 | 0 | 0 | 1 | |
| 3 | 0 (0%) | 0 | 0 | 0 | 0 | |
| 4 | 2 (8%) | 0 | 1 | 0 | 1 | |
| Unknown | 10 (40%) | 7 | 3 | 0 | 0 | |
| Immunologic disease | 6 (24%) | 4 | 2 | 0 | 0 | 0.89 |
| Recurrence | 5 (20%) | 3 | 1 | 0 | 1 | 0.78 |
| Local | 1 (4%) | 0 | 0 | 0 | 1 | 0.2 |
| Nodal | 4 (16%) | 2 | 1 | 0 | 1 | 0.72 |
| Distant | 3 (12%) | 2 | 0 | 0 | 1 | 0.4 |
| Clinical status | 0.45 | |||||
| NED | 15 (60%) | 7 | 5 | 1 | 2 | |
| AWD | 2 (8%) | 0 | 1 | 1 | 0 | |
| DOD | 4 (16%) | 3 | 0 | 0 | 1 | |
| DOC | 4 (16%) | 2 | 2 | 0 | 0 | |
Abbreviations: AWD=alive with disease; DOC=died of other causes; DOD=died of disease; MCV=Merkel cell virus; NED=no evidence of disease.
P-values are based on Fisher's exact test for discrete variables and Wilcoxon rank-sum test for continuous variables.