Table 1.
Baseline Demographic and Clinical Characteristic of Patients with Regard to -C148T FGB Polymorphism
| Demographic and clinical data | CC (n = 142) | CT+TT (n = 101) | p Value |
|---|---|---|---|
| Age, years | 64.34 ± 0.69 | 65.27 ± 0.82 | 0.39 |
| Male gender, n (%) | 109 (77) | 76 (75) | 0.68 |
| BMI, kg/m2 | 27.85 ± 0.34 | 28.17 ± 0.4 | 0.55 |
| Current smokers, n (%) | 38 (27) | 29 (29) | 0.78 |
| Hypertension, n (%) | 122 (86) | 85 (84) | 0.68 |
| Diabetes, n (%) | 37 (26) | 33 (33) | 0.3 |
| COPD, n (%) | 10 (7) | 3 (3) | 0.17 |
| Previous MI, n (%) | 114 (80) | 83 (82) | 0.71 |
| Medications | |||
| ASA, n (%) | 21 (15) | 2 (2) | 0.25 |
| Statins, n (%) | 129 (91) | 96 (95) | 0.28 |
| β-blockers, n (%) | 131 (92) | 87 (86) | 0.12 |
| ACE inhibitors, n (%) | 124 (87) | 87 (86) | 0.89 |
| Laboratory parameters | |||
| Glucose, mmol/L | 5.51 ± 0.11 | 6.12 ± 0.65 | 0.07 |
| Creatinine, μmol/L (n = 144) | 86.56 ± 2.36 | 77.60 ± 2.88 | 0.02 |
| TC, mmol/L | 4.69 ± 0.09 | 4.59 ± 0.11 | 0.45 |
| HDL-C, mmol/L | 1.24 ± 0.02 | 1.2 ± 0.03 | 0.35 |
| LDL-C, mmol/L | 2.96 ± 0.08 | 2.90 ± 0.09 | 0.46 |
| TG, mmol/L | 1.61 ± 0.09 | 1.85 ± 0.1 | 0.07 |
| CRP, mg/L | 4.26 ± 1.01 | 7.49 ± 1.2 | 0.04 |
| Fbg, g/L | 4.07 ± 0.11 | 4.42 ± 0.14 | 0.04 |
Values are given as mean ± SD or number (percentage)
ACE angiotensin-converting enzyme, ASA acetylsalicylic acid, BMI body mass index, MI myocardial infarction, CRP C-reactive protein, COPD chronic obstructive pulmonary disease, Fbg fibrinogen, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides