Fig. 9.

Estimating the release time course directly from the first latency distribution. (A–D) The plots show the bias in estimating the parameters depicted in Fig. 1 when they are obtained from the first latency curve over a range of failure probabilities, calculated using the analytical model. The fractional errors are plotted as a function of the failure probability, for synapses with a number of vesicles ranging from 2 to 100. The black dotted lines indicate an error of 5%.