Table 1.
Characteristics of men from British Heart Foundation Family Heart Study (BHF-FHS) and West of Scotland Coronary Prevention Study (WOSCOPS) stratified by case-control status
| Cases | Controls | p value | |
|---|---|---|---|
| BHF-FHS | |||
| n | 811 | 633 | .. |
| Age (years) | 60·6 (7·5) | 45·5 (11·7) | <0·0001 |
| WOSCOPS | |||
| n | 482 | 1052 | .. |
| Age (years) | 56·9 (5·1) | 56·8 (5·2) | 0·533 |
| Body-mass index (kg/m2) | 26·0 (3·2) | 25·6 (3·2) | 0·026 |
| Systolic blood pressure (mm Hg) | 139·5 (17·2) | 135·7 (17·1) | 0·0001 |
| Diastolic blood pressure (mm Hg) | 85·5 (10·5) | 83·7 (10·2) | 0·001 |
| HDL cholesterol (mmol/L) | 1·1 (0·2) | 1·1 (0·3) | <0·0001 |
| LDL cholesterol (mmol/L) | 5·0 (0·5) | 4·9 (0·4) | 0·004 |
| Triglycerides (mmol/L) | 2·1 (1·6 to 2·8) | 1·9 (1·5 to 2·6) | 0·005 |
| Pravastatin-based treatment | 194 (40%) | 539 (51%) | 0·0001 |
| Glucose (mmol/L) | 4·9 (0·7) | 4·8 (0·7) | 0·025 |
| Diabetes | 9 (2%) | 13 (1%) | 0·464 |
| C-reactive protein (mg/L) | 2·7 (1·2 to 4·9) | 1·9 (0·9 to 3·9) | <0·0001 |
| Smoking | 258 (54%) | 581 (55%) | 0·571 |
| Alcohol consumption ≥20 units per week | 79 (16%) | 186 (18%) | 0·584 |
| Carstairs deprivation index* | 0·4 (−1·7 to 3·0) | 0·5 (−1·8 to 3·0) | 0·943 |
| Highest educational attainment† | 1·6 (0·9) | 1·7 (0·9) | 0·784 |
| In employment | 304 (63%) | 690 (66%) | 0·338 |
Data are n (%), mean (SD), or median (IQR).
*
Continuously scored measure based on four factors: lack of car ownership; Registrar General's Social Class classification of IV or V; overcrowded households; and male unemployment.
†
Average score based on four categories: secondary school with leaving certificate (no graduation); school leaving certificate (with graduation); further education, but no degree; and university degree or similar.