Table 2.
Characteristics of men from British Heart Foundation Family Heart Study (BHF-FHS) and West of Scotland Coronary Prevention Study (WOSCOPS) stratified by Y chromosome haplogroup status
| Haplogroup I | Other haplogroups | p value | |
|---|---|---|---|
| BHF-FHS | |||
| n | 246 | 1198 | .. |
| Age (years) | 55·8 (11·2) | 53·6 (12·3) | 0·006 |
| WOSCOPS | |||
| n | 228 | 1306 | .. |
| Age (years) | 57·3 (5·2) | 56·7 (5·2) | 0·133 |
| Body-mass index (kg/m2) | 25·6 (3·7) | 25·8 (3·1) | 0·469 |
| Systolic blood pressure (mm Hg) | 138·0 (15·9) | 136·7 (17·4) | 0·284 |
| Diastolic blood pressure (mm Hg) | 84·2 (10·1) | 84·2 (10·4) | 0·987 |
| HDL cholesterol (mmol/L) | 1·1 (0·3) | 1·1 (0·3) | 0·310 |
| LDL cholesterol (mmol/L) | 5·0 (0·5) | 5·0 (0·4) | 0·514 |
| Triglycerides (mmol/L) | 1·9 (1·6 to 2·6) | 1·9 (1·5 to 2·6) | 0·481 |
| Pravastatin-based treatment | 110 (48%) | 623 (48%) | 0·937 |
| Glucose (mmol/L) | 4·9 (0·8) | 4·8 (0·7) | 0·243 |
| Diabetes | 6 (3%) | 16 (1%) | 0·179 |
| C-reactive protein (mg/L) | 2·1 (1·1 to 4·0) | 2·1 (1·0 to 4·3) | 0·659 |
| Smoking | 115 (50%) | 724 (55%) | 0·185 |
| Alcohol consumption ≥20 units per week | 34 (15%) | 231 (18%) | 0·353 |
| Carstairs deprivation index* | 0·1 (−1·9 to 2·8) | 0·5 (−1·7 to 3·0) | 0·087 |
| Highest educational attainment† | 1·7 (0·9) | 1·6 (0·9) | 0·189 |
| In employment | 156 (68%) | 838 (64%) | 0·214 |
Data are n (%), mean (SD), or median (IQR).
*
Continuously scored measure based on four factors: lack of car ownership; Registrar General's Social Class classification of IV or V; overcrowded households; and male unemployment.
†
Average score based on four categories: secondary school with leaving certificate (no graduation); school leaving certificate (with graduation); further education, but no degree; and university degree or similar.