Table 4.
Demographic and clinical information for patients with amyotrophic lateral sclerosis with co-morbid frontotemporal dementia
| Patients without the C9orf72 repeat expansion (n=20) | Patients with the C9orf72 repeat expansion (n=10) | p value | |
|---|---|---|---|
| Age at onset (years) | |||
| Mean | 64·8 (9·5) | 57·4 (8·1) | 0·045 |
| Median | 65·6 (56·7–72·5) | 58·2 (55·9–62·8) | 0·100 |
| Age at diagnosis (years) | |||
| Mean | 65·9 (9·7) | 58·7 (7·9) | 0·053 |
| Median | 66·9 (57·5–74·2) | 59·8 (56·9–63·9) | 0·100 |
| Site of onset | |||
| Bulbar | 10 (50%) | 1 (10%) | 0·049 |
| Spinal | 10 (50%) | 9 (90%) | .. |
| Sex | |||
| Male | 13 (65%) | 7 (70%) | 1·000 |
| Female | 7 (35%) | 3 (30%) | .. |
| Type of frontotemporal dementia | |||
| Behavioural | 15 (75%) | 10 (100%) | 0·143 |
| Language variant | 5 (25%) | 0 (0%) | .. |
Data are mean (SD), median (IQR), or number (%).