Table 3.
Specificity of the different diagnostic assays for all patients with tuberculosis whose cultures were negative
|
Sputum AFB |
ELISA |
Determine TB-LAM |
Determine TB-LAM and sputum AFB |
Xpert MTB/RIF (1 sample) |
Determine TB-LAM and Xpert MTB/RIF |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Negative | Specificity | Negative | Specificity | Negative | Specificity | Negative | Specificity | Negative | Specificity | Negative | Specificity | |
| All (n=431) | 430 | 99·8% (98·7–100) | 423 | 98·1% (96·4–99·2) | 425 | 98·6% (97·0–99·5) | 424 | 98·4% (96·7–99·3) | 427 | 99·1% (97·6–99·7) | 421 | 97·7% (95·8–98·9) |
Data are number and sensitivity (95% CI). AFB=acid-fast bacilli. TB=tuberculosis. LAM=lipoarabinomannan. MTB/RIF=Mycobacterium tuberculosis/rifampicin.