Table 1.

Variables included in weight models, Women’s Health Initiative estrogen-plus-progestin randomized trial

No.	Variables	Categories	Baseline	Time-varying
1	Randomization status in the diet-modification trial	Yes/No	Yes	No
2	Age	Five-year category	Yes	No
3	Region	Northeast, South, Midwest, West	Yes	No
4	Race/ethnicity	White, African-American, Hispanic, other	Yes	No
5	Education	High school or less, some college or associate degree, college graduate and above	Yes	No
6	Marital status	Never married, divorced or separated, widowed, presently married or married-like relationship	Yes	No
7	Cigarette smoking	Never, past, current	Yes	Yes
8	Physical activity	Quartiles of metabolic equivalent units/week	Yes	Yes
9	Alcohol intake	None, past, <1 drink/month, <1 drink/week, 1–7 drinks/week, >7 drinks/week	Yes	Yes
10	Body mass index	<25, 25–29, 30–34, 35–39, ≥40 kg/m2	Yes	Yes
11	Age at menarche	<11, 12–13, ≥14 years	Yes	No
12	Number of term pregnancies	Never pregnant, never had term pregnancy, 1–2, 3–4, ≥5	Yes	No
13	Number of children breastfed	0, 1–2, ≥3	Yes	No
14	Age at first birth	Never pregnant/no term pregnancy, <20, 20–29, ≥30 years	Yes	No
15	Family history of breast cancer	Yes/No	Yes	No
16	Family history of fracture	Yes/No	Yes	No
17	Personal history of benign breast diseases	Yes/No	Yes	Yes
18	Personal history of cancer	Yes/No	Yes	Yes
19	Personal history of fracture	Yes/No	Yes	Yes
20	Personal history of osteoporosis	Yes/No	Yes	Yes
21	Personal history of cardiovascular diseases	Yes/No	Yes	Yes
22	Personal history of diabetes	Yes/No	Yes	Yes
23	Oophorectomy (unilateral or bilateral)	Yes/No	Yes	Yes
24	General health	Excellent, very good, good, poor/fair	Yes	Yes
25	Physical functioning construct	Quartiles of quality of life subscale on physical functioning in the RAND36-Item Health Survey	Yes	Yes
26	Prior hormone use	None, <5 years, 5–9 years, ≥10 years	Yes	No
27	Use of oral contraceptives ever	Yes/No	Yes	No
28	Fruit intake	Quartiles of daily intake	Yes	No
29	Vegetable intake	Quartiles of daily intake	Yes	No
30	Mammogram	Yes/No	Yesa	Yes
31	Breast exam	Yes/No	No	Yes
32	Breast biopsy	Yes/No	No	Yes
33	Results from mammogram/breast exam	Normal/benign change, possibly malignant/cancer	No	Yes
34	Number of screening/diagnostic procedures	0, 1, 2, 3, 4, 5, ≥6	Yes	Yes
35	Years since menopause	<10, 10–19, ≥20 years	Yes	No
36	Vasomotor symptoms	None, mild, moderate/severe	Yes	Yes
37	Other menopausal symptoms	Quartiles of summary score of 15 menopausal symptoms	Yes	Yes
38	Changes in breastsb	Yes/No	No	Yes
39	Breast tenderness	None, mild, moderate/severe	No	Yes
40	Vaginal bleeding	None, spotting, light, moderate, severe	No	Yes

^aMammogram in last two years

^bIncludes new lumps, nipple discharge, and skin changes