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Viability of SGO1 mutant mice
| SGO1+/− X SGO1+/− | |||
| Genotype of F1 | SGO1+/+ | SGO1+/− | SGO1−/− |
| Observed frequency | 32.5% (26) | 67.5% (54) | 0 |
| Expected frequency | 25% | 50% | 25% |
SGO1+/− mice were crossed and genotype of the F1 was tested. Among total 80 F1 mice, 26 were SGO1+/+ mice, 54 were SGO1+/− mice but there was no SGO1−/− mice, indicating that SGO1−/− is lethal and did not allow live birth.
