Table 1.

Characteristics of various CRC cell lines

Cell line	Pathological feature	Source	K-RAS	BRAF	PIK3CA	PTEN	p53
CACO-247	Poorly differentiated	Original tumor	wt	wt	N/A	wt	null
COLO-205*	Dukes' type D†	Ascites fluid	wt	mut	wt	wt	mut
DLD-1*	Dukes' type C†	Original tumor	mut	wt	mut	wt	mut
HCT116*	Poorly differentiated	Original tumor	mut	wt	mut	wt	wt
HT29*	Moderately well-differentiated	Original tumor	wt	mut	mut	wt	mut
KM-1248	Dukes' type B, poorly differentiated	Original tumor	mut	wt	wt	mut	mut
LOVO49	Dukes' type C, grade IV†	Metastatic site (left supraclavicular region)	mut	wt	wt	N/A	wt
RKO*	Poorly differentiated	Original tumor	wt	mut	mut	wt	wt
SW1116*	Dukes' type A, grade III†	Original tumor	mut	wt	wt	wt	mut
SW48*	Dukes' type C, grade IV†	Original tumor	wt	wt	wt	wt	wt
SW620*	Dukes' type C†	Lymph node metastasis	mut	wt	wt	wt	mut
SW480†50	Dukes' type B	Original tumor	mut	wt	wt	wt	mut

N/A, not available. Wt, wild type. Mut, mutant; *Information from www.sanger.ac.uk/genetics/CGP/cosmic.

^†Information from www.atcc.org.