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. 2012 Apr;139(4):285–294. doi: 10.1085/jgp.201110764

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© 2012 Cenedese et al.

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Figure 7. — Ca²⁺ sensitivity of TMEM16B mutants. Conductance density calculated from tail currents measured at −100 mV after prepulses between −100 and +100 mV as indicated was plotted versus [Ca²⁺]_i for E367Q (A; n = 3–6), ΔE₅ (B; n = 3–5), and ΔEYE (C; n = 3–8) mutants. Lines are the fit to the Hill equation (Eq. 1). (D) K_1/2 values plotted versus voltage for each mutant.