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. 2012 Apr;139(4):295–304. doi: 10.1085/jgp.201110725

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© 2012 Tan et al.

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Figure 3. — Comparison of TEA inhibition between Kcv and substitutions L70Y and L70A. 150 mM KCl buffered with 10 mM Tris, pH 7.2. (A) IC₅₀ at various voltages for wt-Kcv, cis TEA (closed circles); L70Y, cis TEA (closed boxes); L70A, cis TEA (closed triangles); wt-Kcv, trans TEA (open circles); L70Y, trans TEA (open boxes); and L70A, trans TEA (open triangles). (B) Vertical bar comparison of TEA sensitivity from the cis and trans sides at ±60 mV for wt-Kcv, L70Y, and L70A. Data points are presented as mean ± SD.