Table 1.
Scoring Criteria of Eye Irritative Reaction
| Ocular Reaction | Score |
|---|---|
| Cornea | |
| No opacity | 0 |
| Scatter or disseminated opacity, iris clearly seen | 1 |
| Translucent area distinguishable, iris blurred and indistinct | 2 |
| Grey translucent area appeared, iris indistinct, pupil merely seen | 3 |
| Cornea opacity, iris inrecognizable | 4 |
| Iris | |
| Normal | 0 |
| Iridial folds deepen, congestion, slight congestion around cornea, pupil reative to light | 1 |
| Hemorrhage/macroscopic necrosis/ unreactive to light | 2 |
| Conjunctiva | |
| Congestion (including palpebral conjunctiva and in palpebral conjunctiva) | |
| Normal capillary | 0 |
| Capillary congestion with bright red colour | 1 |
| Capillary congestion with bright red colour, vascular inrecognizable | 2 |
| Disseminated congestion with purple red colour | 3 |
| Edema | |
| Absence | 0 |
| Slightly edema (eyelids including) | 1 |
| Significant edema with eyelid ectropion | 2 |
| Significant edema with eyelid half closure | 3 |
| Significant edema with eyelid more than half closure | 4 |
| Exudates | |
| Absence | 0 |
| Minor | 1 |
| Enough to wet or adhere the eyelid and eyelash | 2 |
| Enough to wet or adhere the entire ocular area | 3 |
| Maximum total scores | 16 |