Table 1.
Patient characteristics, overall and by ECLS status
| Variable | Overall | ECLS | p-Value* | |
|---|---|---|---|---|
| N = 113 | Yes (N = 50) | No (N = 63) | ||
| Survival to ICU discharge, N (%) | 50 (44) | 16 (32) | 34 (54) | 0.0195 |
| Age (months), median (IQR) | 19 (0.2, 181) | 0.8 (0, 10) | 151 (19, 213) | <0.0001 |
| Sex: female, N (%) | 46 (40.7) | 20 (40) | 26 (41.3) | 0.8915 |
| Hospital days prior to CRRT, median (IQR) | 6 (2, 16) | 6 (3, 13) | 4 (2, 17) | 0.3491 |
| ICU days prior to CRRT, median (IQR) | 3 (2, 6) | 4 (3, 11) | 2 (1, 6) | 0.0015 |
| Vasoactive medications at initiation, N (%) | 85 (75) | 47 (94) | 38 (60.3) | <0.0001 |
| >2 vasoactive medications at initiation, N (%) | 46 (40.7) | 31 (62) | 15 (23.8) | <0.0001 |
| Number of vasoactive agents at initiation, median (IQR) | 2 (1, 3) | 3 (2, 4) | 1 (0, 2) | <0.0001 |
| Diuretic exposure, N (%) | 81 (71.7) | 45 (90) | 36 (57.1) | <0.0001 |
| Diuretic infusion, N (%) | 51 (45.1) | 33 (66) | 18 (28.6) | <0.0001 |
| Mechanical ventilation at initiation, N (%) | 98 (86.7) | 50 (100) | 48 (76.2) | 0.0002 |
| Therapeutic plasma exchange, N (%) | 19 (16.8) | 8 (16) | 11 (17.5) | 0.8367 |
| Patients qualifying as failure by RIFLE, N (%) | 67 (59.3) | 28 (56) | 39 (61.9) | 0.5257 |
| Patients qualifying as failure by pRIFLE, N (%) | 59 (52.2) | 25 (50) | 34 (54) | 0.6749 |
| PRISM III score at ICU admission, median (IQR) | 13.0 (7, 18) | 16 (9, 21) | 11 (7, 15) | 0.0085 |
ECLS extracorporeal life support, CRRT continuous renal replacement therapy
*
Comparisons are between ECLS and non-ECLS groups