Table 1.
Baseline characteristics of HOST participants by race
| Characteristic | Non-Hispanic White (n=873) | Non-Hispanic Black (n=624) | P Value |
|---|---|---|---|
| Age (yr) | 69±10.6 | 61±12.0 | <0.001 |
| Male | 856 (98) | 612 (98) | 0.80 |
| eGFR (ml/min per 1.73 m2) | |||
| >15 | 575 (66) | 280 (45) | 0.01 |
| <15 not on dialysis | 47 (5) | 10 (2) | 0.02 |
| ESRD | 251 (29) | 334 (53) | <0.001 |
| Causes of renal disease | |||
| diabetes | 326 (37) | 267 (43) | <0.001 |
| hypertension | 256 (29) | 230 (37) | |
| GN | 50 (6) | 36 (5) | |
| obstructive uropathy | 21 (3) | 7 (1) | |
| polycystic kidney disease | 38 (4) | 12(2) | |
| othera | 182 (21) | 72 (12) | |
| Current smoker | 175 (20) | 150 (24) | 0.04 |
| BMI (kg/m2) | 27.8±4.9 | 27.5±5.4 | 0.14 |
| Systolic BP (mmHg) | 141±23 | 143±24 | 0.02 |
| Diastolic BP (mmHg) | 72±13 | 78±13 | <0.001 |
| Diabetes | 437 (50) | 349 (56) | 0.02 |
| Hypertension | 838 (96) | 599 (96) | 0.96 |
| Cardiovascular disease | 533 (61) | 293 (47) | <0.001 |
| Charlson score | 4.95±2.20 | 4.92±2.21 | 0.84 |
| Medication | |||
| ACE inhibitor | 323(37) | 275(44) | 0.01 |
| ARB | 114 (13) | 69 (11) | 0.27 |
| β blocker | 559 (64) | 331 (53) | <0.001 |
| lipid-lowering agent | 498 (57) | 243 (39) | <0.001 |
All values are expressed as mean ± SD or n (%). BMI, body mass index; ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker.
a
Other includes tubulointerstitial disease, vascular disease, and unknown causes.