Table 5.
KEGG significant terms up-regulated in ob/ob vs. WT, without significant changes in POKO vs. WT mice
| Term | Name | Term size | Odds ratio log | Adj. p-value |
|---|---|---|---|---|
| mmu00604 | Glycosphingolipid biosybthesis | 21 | 1.86 | 2.43E-02 |
| mmu04940 | Type 1 diabetes | 54 | 1.83 | 2.96E-05 |
| mmu05330 | Allograt rejection | 48 | 1.79 | 1.24E-04 |
| mmu05332 | Graft-verus host disease | 50 | 1.74 | 1.63E-04 |
| mmu05320 | Autoinmune thyroid disease | 63 | 1.71 | 3.08E-05 |
| mmu04514 | Cell adhesion molecules | 141 | 1.65 | 2.05E-10 |
| mmu05416 | Viral myocarditis | 80 | 1.23 | 5.78E-03 |
| mmu04730 | Long term depresion | 74 | 1.14 | 2.51E-02 |
| mmu04270 | Vascular smooth muscle contact | 126 | 1.12 | 1.43E-03 |
KEGG significant terms up-regulated in islets from ob/ob vs. WT mice (adjusted p-value ≤ 0.05), without significant changes in islets from POKO vs. WT mice.