Table 9.
KEGG significant terms up-regulated in POKO vs. ob/ob mice
| ID | Term |
|---|---|
| mmu04740 | Olfactory transduction |
| mmu03040 | Spliceosome |
| mmu04810 | Regulation of actin cytoskeleton |
| mmu04530 | Tight junction |
| mmu04520 | Adherens junction |
| mmu03050 | Proteasome |
| mmu03010 | Ribosome |
| mmu05219 | Bladder cancer |
| mmu04512 | ECM-receptor interaction |
| mmu05200 | Pathways in cancer |
| mmu04670 | Leukocyte transendothelial migration |
| mmu04115 | p53 signaling pathway |
| mmu03020 | RNA polymerase |
| mmu04020 | Calcium signaling pathway |
| mmu00270 | Cysteine and methionine metabolism |
| mmu00260 | Glycine, serine and threonine metabolism |
| mmu00830 | Retinol metabolism |
| mmu00240 | Pyrimidine metabolism |
| mmu04510 | Focal adhesion |
| mmu00900 | Terpenoid backbone biosynthesis |
| mmu00100 | Steroid biosynthesis |
| mmu00450 | Selenocompound metabolism |
| mmu00480 | Glutathione metabolism |
| mmu04012 | ErbB signaling pathway |
| mmu04360 | Axon guidance |
| mmu03420 | Nucleotide excision repair |
| mmu04621 | NOD-like receptor signaling pathway |
| mmu04144 | Endocytosis |
| mmu04540 | Gap junction |
| mmu00330 | Arginine and proline metabolism |
| mmu04010 | MAPK signaling pathway |
| mmu04062 | Chemokine signaling pathway |
| mmu04110 | Cell cycle |
| mmu00970 | Aminoacyl-tRNA biosynthesis |
| mmu04350 | TGF-beta signaling pathway |
| mmu00230 | Purine metabolism |
| mmu03030 | DNA replication |
| mmu00250 | Alanine, aspartate and glutamate metabolism |
| mmu00561 | Glycerolipid metabolism |
| mmu04060 | Cytokine-cytokine receptor interaction |
| mmu00520 | Amino sugar and nucleotide sugar metabolism |
| mmu00290 | Valine, leucine and isoleucine biosynthesis |
| mmu00052 | Galactose metabolism |
| mmu00040 | Pentose and glucuronate interconversions |
| mmu03018 | RNA degradation |
| mmu03320 | PPAR signaling pathway |
KEGG significant terms up-regulated in islets from POKO vs. ob/ob mice (adjusted p-value ≤ 0.05)