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. 2012 Mar 29;8(3):e1002596. doi: 10.1371/journal.pgen.1002596

Figure 4. USP binds to similar genomic locations in nurse and forager fat bodies.

Figure 4

The genomic binding sites of USP were assessed in 3 biological replicates each from nurse and forager fat bodies. A. Comparison of the intensity with which USP bound each of its 1360 binding sites in nurses and foragers. Normalized, log2-transformed fold differences in binding intensity and the significance of these differences (ANOVA) are shown. We observed no dramatic differences in USP binding at any of these sites between nurse and forager samples. B. Differences in USP binding between nurses and foragers were uncorrelated with the expression of nearby genes in nurses and forager fat bodies. Data are shown for 116 genes located near genomic binding sites of USP that had >1.25-fold difference in binding intensity between nurses and foragers. C. Fold change responses to usp RNAi and maturation are weakly correlated. Data are shown for the 29 genes that responded significantly to both. Each circle represents a single gene. Genes represented by closed circles also responded to juvenile hormone analog treatments.