Table 2. Deletion of C. elegans clp-1 partially suppresses dystrophin-based muscle degeneration.
| Genotype | Abnormal body wall muscle cellsa |
| crIs4 wildtype-like | 0.2±0.1 |
| crIs4 Unc | 11.0±1.0 |
| crIs4 paralysed | 33.8±0.6 |
| clp-1(tm690) | 0.0±0 |
| dys-1(cx18);hlh-1(cc561ts) | 10.9±0.4 |
| dys-1(cx18);hlh-1(cc561ts); clp-1(tm690) | 5.9±0.6b |
a
Worms were grown at 15°C, and scored as Day 2 adults. Following phalloidin staining, the 20 most central muscle cells from each of the two most visible body wall muscle quadrants were scored (40 cells per animal), as described in Gieseler et al. (2000). Number represents the mean ± standard deviation from 3 independent experiments involving at least 30 animals per experiment.
b
Reduction is significantly different based from dys-1(cx18); hlh-1(cc561ts) based on Student's t-test (P<0.001).