Table 3. Coreferentialities with CD25^bright/CD4⁺ frequencies.

Within Group	SLE Patients		Unaff. Relatives		Controls
	RC	PPerm *	RC	PPerm *	RC	PPerm *
Recognized IgG bands to HEp2-cytoplasmic proteins	−0.13	0.491	+0.61	<0.001	+0.04	0.792
Recognized IgG bands to HEp2-nuclear proteins	−0.14	0.498	+0.36	0.257	+0.23	0.232
Recognized IgG bands to human brain proteins	+0.20	0.375	+0.24	0.694	−0.04	0.794
log IgG anti-dsDNA	−0.12	0.589	+0.59	0.019	−0.03	0.904
log IgG anti-Ro60/SSA	−0.16	0.314	+0.74	0.002	+0.18	0.185
log IgG anti-Sm	−0.03	0.848	+0.48	0.005	+0.00	0.987
log IgG anti-nRNP	−0.09	0.635	+0.30	0.212	+0.13	0.401
log IgM anti-dsDNA	−0.17	0.557	+0.34	0.055	+0.30	0.066

^*Significance according to permutation test (see methods). Effects of bystander coreferentiality were checked for all significant tests (see methods), but rates of simulated bystander data reaching the respective test significance never exceeded 5%.