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. 2012 Mar 29;7(3):e33992. doi: 10.1371/journal.pone.0033992

Table 4. Coreferentialities of the IL2RA model score with other parameters.

Within Group Unaff. Relatives SLE Patients Controls
(optimized)
RC PPerm RC PPerm RC PPerm
Frequency CD25bright/CD4+ +0.39 0.025 −0.44 0.028 −0.03 0.866
CD247 (CD3Z) All typed SNPs* 0.57 0.118 0.51 0.041 0.57 0.023
log IgG anti-dsDNA −0.03 0.894 +0.36 0.112 +0.09 0.548
log IgG anti-Ro60/SSA +0.03 0.851 +0.21 0.247 +0.11 0.535
log IgG anti-Sm +0.40 0.156 +0.15 0.379 +0.37 0.014
log IgG anti-nRNP +0.34 0.099 +0.22 0.231 +0.37 0.003
log IgM anti-dsDNA +0.05 0.757 +0.49 0.010 −0.17 0.237
Recognized IgG bands to HEp2-cytoplasmic proteins +0.14 0.574 +0.06 0.749 +0.28 0.067
Recognized IgG bands to HEp2-nuclear proteins +0.36 0.030 +0.32 0.084 −0.28 0.066
Recognized IgG bands to brain proteins −0.04 0.947 −0.06 0.696 +0.29 0.057
HLA-DRB1*01 Alleles −0.56 0.007 +0.18 0.416 (not typed)
HLA-DRB1*03 Alleles +0.25 0.282 +0.04 0.817 (not typed)
HLA-DRB1*04 Alleles +0.62 0.006 +0.00 0.978 (not typed)
HLA-DRB1*07 Alleles −0.37 0.097 −0.18 0.372 (not typed)
HLA-DRB1*11 Alleles +0.33 0.129 +0.37 0.128 (not typed)
HLA-DRB1*13 Alleles +0.56 0.035 +0.09 0.593 (not typed)
HLA-DRB1*15 Alleles −0.09 0.838 −0.01 0.971 (not typed)
All HLA-DRB1 types* 0.62 0.027 0.37 0.338
*

Test for multiple parameters, on maximal absolute coreferentiality |RC|max (see methods). Significant tests, except those for multiple SNPs, were also checked for the effect of bystander coreferentiality (see methods), but no such effect was detected.