Table 4. In vivo responses of ALL xenografts to ATO, VXL or VXL/ATO combination treatments.

Xenograft	Treatment	Median EFS [days] (number of mice)	LGD [days]	Significance vs control [P value]	Significance vs VXL [P value]
ALL-4	Control	5.1 (8)	-
	ATO	10.5 (8)	5.4	0.0075
	VXL	40.3 (7)	35.2	0.0001
	VXL/ATO	42.3 (7)	37.2	0.0001	0.0252
ALL-7	Control	11.5 (7)	-
	ATO	10.8 (7)	0	0.6734
	VXL	63.3 (6)	51.8	0.0004
	VXL/ATO	70.8 (7)	59.3	0.0001	0.0012
ALL-8	Control	10.3 (7)	-
	ATO	12.4 (7)	2.1	0.6399
	VXL	65.6 (7)	55.3	0.0001
	VXL/ATO	68.4 (6)	58.1	0.0004	0.1499
ALL-19	Control	9.3 (7)	-
	ATO	11.9 (9)	2.6	0.115
	VXL	55.2 (8)	45.9	0.0270
	VXL/ATO	52.9 (9)	43.6	0.0015	0.9394

Significant values are shown in bold.