Figure 7. H&E analysis of tumor tissues treated with HIFU in the presence or absence of Gd-C₅F₁₂-PLN-100.

The staining was performed on paraffin-imbedded specimens (upper panel). The dotted area represents the ablated tumor tissue. The ablated area perpendicular to the HIFU direction was measured and shown with histogram (lower panel). *P<0.025, the Gd-C₅F₁₂-PLN-100 significantly increased the HIFU-induced tumor ablation (n = 6).