Table 3. Multivariate analysis of Overall Survival: Adjusted hazards ratio (HR) of mortality, 95% Confidence Intervals (CI), and p values.

Characteristics	HR	95% CI	p value
Age in years (ref: ≤65)
age>65	1.64	1.02–2.63	0.04
Karnofsky Performance Score (ref: KPS≥80)
KPS<80	3.57	2.20–5.79	<.0001
Low vs. high extent of resection	1.39	0.89–2.17	0.14
Lack of Standard Treatment	3.98	2.38–6.65	<.0001
PTEN loss	1.31	0.85–2.03	0.22