Nomenclature | P2X1 | P2X2 | P2X3 | P2X4 |
---|---|---|---|---|
Ensembl ID | ENSG00000108405 | ENSG00000187848 | ENSG00000109991 | ENSG00000135124 |
Potent agonists | L-βγ-meATP, αβ-meATP, BzATP | – | αβ-meATP, BzATP | – |
Potent antagonists | TNP-ATP (pIC50 8.9, Virginio et al., 1998), Ip5I (pIC50 8.5), NF023 (pIC50 6.7); NF449 (pIC50 6.3, Kassack et al., 2004) | – | TNP-ATP (pIC50 8.9, Virginio et al., 1998), AF353 (pIC50 8.0, Gever et al., 2010), A317491 (7.5, Jarvis et al., 2002), RO3 (pIC50 7.5, Ford et al., 2006) | – |