Table 1.
The values of measured biochemical parameters in patients with ESRD and in the control group
| Parameter | Unit | ESRD patients | Control group | Reference range | p |
|---|---|---|---|---|---|
| Median (range) | Median (range) | ||||
| Haemoglobin | g/dl | 12.05 (8.4–16.1) | 14.30 (12.80–16.00) | 11–17 | <0.01 |
| White blood count | 103/μl | 5.93 (3.83–14.04) | 6.24 (4.15–7.71) | 4–10 | NS |
| Albumin | g/l | 41 (33–56) | 45 (45–50) | 35.0–50.0 | <0.01 |
| Creatinine | μmol/l | 745.2 (270.3–1134.6) | 60.15 (42.80–99.6) | 45.0–97.0 | <0.01 |
| Urea nitrogen | mmol/l | 18.50 (12.50–34.80) | 4.85 (3.4–6.9) | 1.7–8.3 | <0.01 |
| Phosphate | 1.69 (1.07–2.78) | 1.11 (0.77–1.41) | 0.87–1.45 | <0.01 | |
| Total calcium | 2.20 (1.80–2.56) | 2.36 (2.28–2.32) | 2.02–2.61 | 0.02 | |
| Fibrinogen | g/l | 6.36 (2.50–8.70) | 2.76 (2.1 3–3.81) | 1.8–3.5 | <0.01 |
| C-reactive protein (CRP) | mg/l | 3.87 (0.26–30.30) | 0.98 (0.21–5.1) | 0 – 3 | 0.02 |
| Interleukin-6 (IL-6) | pg/ml | 2.645 (0.67–19.81) | 0.52 (0.27–1.85) | 0.447–9.96 | <0.01 |
| Soluble IL-2 receptor (sIL-2R) | 2,987.5 (1,535–5,739) | 893 (699–1323) | 458–1997 | 0.01 | |
| Soluble intercellular adhesion molecule-1 (sICAM-1) | ng/ml | 304 (210–484) | 229.07 (194.35–283.63) | 115–306 | 0.01 |
| Amyloid A (SAA) | mg/l | 5.7 (1.7–145) | 2.3 (0.90–9.7) | 5.0–6.4 | 0.01 |
| Interleukin-18 (IL-18) | pg/ml | 522.7 (318.4–1437.2) | 286.35 (167.5–449.5) | 37–215 | <0.01 |
| Antibodies to human heat shock protein 60 (aHSP60) | ng/ml | 29.21 (8.54–267.32) | 23 (16.66–46.50) | No data | NS |
| Soluble CD40 ligand (sCD40L) | 9.39 (2.92–17.74) | 14.49 (7.62–22.11) | 1.13–3.13 | <0.01 | |
| Asymmetric dimethylarginine (ADMA) | μmol/l | 0.923 (0.267–1.476) | 0.579 (0.348–0.968) | 0.26–0.64 | 0.047 |
| Homocysteine | 24.8 (8.5–67.2) | 10.95 (5.3–17) | 3.6–15.0 | <0.01 | |
| Anti-oxidized LDL | 163.25 (65.26–1200) | 158.75 (37–1200) | No data | NS | |
| HDL cholesterol | mmol/l | 1.24 (0.86–2.35) | 1.30 (1.03–2.04) | 0.9–3.00 | NS |
| LDL cholesterol | 2.6 (1.49–5.42) | 3.17 (2.4–6.3) | 0.2–3.40 | NS | |
| Triglycerides | 1.805 (0.9–3.35) | 1.39 (0.94–4.83) | 0.2–2.30 | <0.01 | |
| Adiponectin | ng/ml | 16,846.5 (3,437–43,497) | 5,867 (4,080–13,346) | 865–21424 | <0.01 |
| Apolipoprotein A-I (apoA-I) | g/l | 1.55 (1.03–2.08) | 1.66 (1.37–2.05) | W 1.25–2.15 | NS |
| M 1.10–2.05 | |||||
| Apolipoprotein B (apoB) | 0.95 (0.56–1.58) | 0.96 (0.68–1.72) | W 0.55–1.25 | NS | |
| M 0.55–1.40 | |||||
| Apolipoprotein B/A-I (apoB/A-I) | – | 0.59 (0.32–1.27) | 0.61 (0.34–0.98) | W 0.3–0.9 | NS |
| M 0.55–1.0 | |||||
| Oxidized LDL | ng/ml | 49.52 (4.13–2340.64) | 41.41 (9.88–259.54) | 18–2261 | NS |
| Body mass index | kg/m2 | 25.40 (19.43–34.60) | 25.01 (20.82–36.57) | 18.5–24.99 | NS |