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. Author manuscript; available in PMC: 2013 Mar 20.
Published in final edited form as: Cancer Cell. 2012 Mar 20;21(3):362–373. doi: 10.1016/j.ccr.2012.02.010

Figure 1. Transgenic gene expression in the sympathetic neurons and the interrenal gland.

Figure 1

(A) Left: Schematic of a transverse section illustrating zebrafish anatomical structures, dorsal upwards. Right: Schematic of a sagittal section illustrating zebrafish anatomical structures, anterior to left.

(B) EGFP expression (green) in the zebrafish chain of sympathetic ganglia (arrowheads), the IRG (arrow) and medulla oblongata (asterisk) at 3 wpf. Lateral view of confocal-brightfield image, anterior to left. The magnified view of the boxed region is shown on the right. Scale bar, 500 μm.

(C) EGFP is coexpressed with TH in the SCG at 6 wpf (sagittal section); TH coexpression is indicated in red. Scale bar, 20 μm.

(D) EGFP is coexpressed with TH in the chain of sympathetic ganglia at 6 wpf (transverse section). TH coexpression is indicated in red. Scale bar, 20 μm.

(E) EGFP is coexpressed with TH in the IRG at 8 months postfertilization (mpf) (sagittal section). TH coexpression is indicated in red. Scale bar, 100 μm.

Ao, aorta; Cb, cerebellum; Chfn, chromaffin cells; E, esophagus; G, gill; H, heart; HK, head kidney; I, intestine; IRG, interregnal gland; KB, kidney body; L, liver; Me, medulla; Nc, notochord; SB, swim bladder; SC, spinal cord; SCG, superior cervical ganglion; Sym.C, sympathetic chain.

See also Figure S1.