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. 2012 Mar 15;12:13. doi: 10.1186/1471-2393-12-13

Table 1.

Overview of the studies published by authors consulted when planning the IPD meta-analysis

Study Period N Intervention Primary outcome
Briery[11] 06/04-06/10 30 250 mg 17-OPHC or placebo delivery before 35 completed weeks' of gestation

Cetingoz[10] 12/04-02/07 67 100 mg vaginal progesterone or placebo delivery before 37 weeks

Lim[12] 08/06-07/09 654 250 mg 17-OHPC in 1 mL castor oil or placebo composite outcome (Severe RDS, BPD, IVH grade III or worse, NEC, proven sepsis or death before discharge)

Combs[7] 11/04-02/10 240 250 mg 17-OHPC or placebo composite outcome (RDS, Oxygen therapy at 28d, Neonatal sepsis, Pneumonia, IVH grade III or worse, periventricular leukomalacia, NEC, retinopathy of prematurity, asphyxia)

Nassar[13] 10/06-10/10 290 250 mg 17-OPHC or placebo frequency of delivery prior to completed 37 weeks of gestation (259 days)

Norman[9] 12/04-04/08 500 Vaginal progesterone gel 90 mg or placebo delivery or intrauterine death before 34 weeks of gestation

Rode[14] 06/06-09/10 650 200 mg vaginal progesterone of placebo incidence of delivery < 34 weeks

Rouse[8] 04/04-02/06 661 250 mg 17-OHPC in 1 mL castor oil or placebo composite outcome (delivery or fetal death before 35 completed weeks of gestation)

Rozenberg[15] 06/06-06/10 160 500 mg 17-OPHC or no treatment Interval between inclusion and delivery

Serra[16] 01/06-05/08 246 200 mg or 400 mg vaginal progesterone or placebo Preterm birth rate (< 37 weeks)