FIG. 2.

Lin⁻ BMCs contribute to mammary gland regeneration when mixed with normal mouse MECs. (A) X-gal stained whole mounts of parous, nonpregnant chimeric mammary outgrowths resulting from inoculation of Lin⁻ BMCs isolated from R26R mice and wild-type MECs (1:1 ratio). (B) Cross section of the same gland shown in (A). (C) X-gal stained whole mount of second-generation outgrowth resulting from transplantation of a fragment taken from Lin⁻ BMC/MECs first-generation chimeric outgrowth. (D) Cross section of the same gland shown in (C). Scale bars: (A) 2 mm; (C) 1.5 mm; (B, D) 150 μm. MECs, mammary epithelial cells. Color images available online at www.liebertonline.com/scd