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. 2012 Apr;28(4):384–392. doi: 10.1089/aid.2011.0175

FIG. 2.

FIG. 2.

Consensus group M Gag-induced IFN-γ responses. The profile of consensus group M Gag-induced T cell recognition is shown (n=50) illustrating cumulative IFN-γ magnitudes (SFU/106 PBMCs) to individual Gag peptides, sequences of the dominantly targeted peptides, and the circulating subject HLA alleles (A). Recognition of consensus group M Gag peptides clusters into eight regions: Gag17–47 (p17-I), Gag74–95 (p17-II), Gag140–194 (p24-I), Gag196–218 (p24-II), Gag245–283 (p24-III), Gag290–381 (p24-IV), Gag290–381 (p24-V), and Gag429–447 (p15-I) and the proportion of individuals targeting peptides within the Gag clusters are illustrated (B).