FIG. 6.

Regulation of the Mmp10 promoter by FSK + PMA in rat granulosa cells. Granulosa cells were isolated from gonadotropin-primed immature rats (48 h post-eCG), transfected with various rat Mmp10 promoter constructs for 24 h, and subsequently cultured with FSK + PMA for 6 h. Relative levels of the promoter activity where normalized to the luciferase:renilla ratio, and data are presented as the relative luciferase activity. Bars with no common superscripts within a promoter construct are significantly different from their respective control (P < 0.05). Inset: data are presented as the fold change in activity relative to the corresponding control. Bars with no common superscripts are significantly different (P < 0.05). Values represent the mean ± SEM (n = 3–4).