Table 1.
Clinical and epidemiological characterization of analyzed patients
| S. aureus PVL(+) n=168 | S. aureus PVL(-) n=56 | ||||||
|---|---|---|---|---|---|---|---|
| Severe invasive infections n=42 | Mild superficial infections n=126 | p | Severe invasive infections n=25 | Mild superficial infections n=31 | p | ||
| Demographics | |||||||
| Median age (months) (min.-max.) | 114(1-214) | 112 (1-214) | 112(1-214) | 0,947 | 142 ( 1- 210) | 87(2-213) | 0,959 |
| Sex (female) | 92 (41,1%) | 16(39,0%) | 51(40,0%) | 0,897 | 11(47,8) | 14(42,4%) | 0,689 |
| Co - morbidities | 42 (18,8%) | 20(48,8%) | 11(8,7%) | <0,001 | 9(39,1%) | 2(6,1%) | 0,004 |
| Source of infection | |||||||
| Community-associated | 176(78,6%) | 24(48,8%) | 124(91,3%) | <0,001 | 13(56,5%) | 27(81,8%) | 0,039 |
| Hospital-associated | 48 (21,4%) | 17(51,0%) | 3(8,7%) | <0,001 | 10(43,5%) | 6(18,2%) | <0,001 |
| Drug resistance | |||||||
| MRSA | 6 (2,7%) | 0 | 3 | 1,000 | 0 | 3 | 0,261 |
| Interventions | |||||||
| Antibiotic therapy | 214(95,5%) | 39(95,1%) | 121(95,3%) | 1,000 | 23(100%) | 31(93,9%) | 0,507 |
| Procedure for infectious source control | 172(75,7%) | 29(72,5%) | 95(74,8%) | 0,771 | 19(82,6%) | 25(78,1%) | 0,745 |
p value for comparison between severe invasive infections and mild superficial infections