. 2012 Feb 28;3(1):66–76.

Table 4.

Hazard Ratio (HR) and 95% Confidence Intervals (CI) for risk of all-cause, cancer-specific, and cardiovascular death, stratified by Charlson comorbidity index. All models were adjusted for age, gender, socio-economic status. *Also adjusted for history of cancer prior to measurement. ^Also adjusted for history of circulatory disease prior to measurement.

	Total			Men			Women

	All cause	Cancer*	Circulatory^	All cause	Cancer*	Circulatory^	All cause	Cancer*	Circulatory^
	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)	HR(95%CI)
Charlson = 0

Score=0	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Score=1	1.40 (1.31-1.49)	1.30 (1.16-1.46)	1.42 (1.28-1.57)	1.33 (1.22-1.44)	1.21 (1.05-1.40)	1.35 (1.18-1.54)	1.51 (1.36-1.67)	1.45 (1.21-1.73)	1.54 (1.32-1.80)
Score=2	2.14 (1.92-2.39)	1.89 (1.57-2.29)	2.18 (1.84-2.58)	2.11 (1.85-2.41)	1.82 (1.44-2.29)	2.33 (1.91-2.85)	2.09 (1.72-2.54)	1.89 (1.32-2.71)	1.67 (1.21-2.31)
Score=3	3.49 (2.74-4.45)	3.39 (2.22-5.18)	3.62 (2.52-5.21)	3.90 (2.91-5.22)	3.22 (1.89-5.49)	4.63 (3.04-7.04)	2.71 (1.74-4.22)	3.57 (1.77-7.18)	1.96 (0.93-4.13)

Charlson = 1

Score=0	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Score=1	1.33 (1.17-1.52)	1.29 (0.95-1.74)	1.25 (1.04-1.49)	1.24 (1.04-1.47)	1.13 (0.76-1.69)	1.31 (1.04-1.65)	1.48 (1.21-1.80)	1.52 (0.95-2.43)	1.14 (0.85-1.53)
Score=2	1.80 (1.49-2.18)	1.37 (0.85-2.20)	2.06 (1.62-2.62)	1.65 (1.30-2.09)	1.10 (0.59-2.06)	1.95 (1.44-2.65)	2.09 (1.52-2.88)	1.90 (0.92-3.90)	2.37 (1.59-3.55)
Score=3	2.49 (1.74-3.56)	1.91 (0.76-4.78)	2.43 (1.50-3.92)	2.45 (1.62-3.69)	1.10 (0.34-3.56)	2.57 (1.50-4.38)	2.18 (1.03-4.62)	15.98 (3.64-70.10)	1.83 (0.58-5.74)

Charlson = 2

Score=0	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Score=1	1.38 (1.20-1.58)	1.08 (0.86-1.36)	1.60 (1.30-1.98)	1.19 (0.98-1.45)	0.80 (0.57-1.13)	1.52 (1.33-2.03)	1.57 (1.30-1.90)	1.41 (1.04-1.92)	1.70 (1.24-2.32)
Score=2	2.22 (2.82-2.72)	2.16 (1.53-3.04)	2.13 (1.55-2.93)	2.02 (1.53-2.67)	2.26 (1.45-3.52)	1.92 (1.25-2.97)	2.43 (1.81-3.26)	2.04 (1.17-3.54)	2.30 (1.43-3.69)
Score=3	3.19 (2.18-4.65)	5.10 (2.83-9.19)	2.69 (1.49-4.86)	2.61 (1.58-4.28)	4.43 (2.03-9.67)	2.01 (0.92-4.39)	4.04 (2.26-7.22)	6.24 (2.54-15.31)	4.21 (1.71-10.36)

Charlson = 3

Score=0	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Score=1	1.27 (0.99-1.61)	1.31 (0.76-2.27)	1.30 (0.93-1.81)	1.05 (0.76-1.45)	0.79 (0.37-1.68)	0.94 (0.61-1.44)	1.56 (1.09-2.23)	2.01 (0.93-4.35)	2.14 (1.28-3.57)
Score=2	1.71 (1.25-2.33)	3.72 (2.02-6.85)	1.35 (0.87-2.10)	1.18 (0.79-1.76)	2.27 (0.96-5.34)	0.98 (0.57-1.67)	3.44 (2.12-5.57)	10.05 (4.11-24.59)	2.51 (1.17-5.39)
Score=3	2.80 (1.57-4.98)	8.69 (2.90-26.05)	2.09 (0.89-4.89)	2.71 (1.38-5.34)	5.90 (1.64-21.17)	1.79 (0.69-4.64)	2.63 (0.82-8.44)	48.72 (5.04-471.16)	1.90 (0.26-14.20)

Charlson = 4

Score=0	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Score=1	1.34 (1.04-1.73)	0.79 (0.46-1.36)	1.67 (1.16-2.40)	1.28 (0.89-1.83)	0.82 (0.39-1.72)	1.60 (0.97-2.64)	1.44 (1.00-2.06)	0.78 (0.35-1.75)	1.82 (1.08-3.10)
Score=2	1.78 (1.32-2.40)	1.47 (0.80-2.70)	1.93 (1.26-2.97)	1.70 (1.13-2.56)	1.82 (0.87-3.79)	1.74 (0.97-3.14)	1.98 (1.26-3.12)	1.05 (0.29-3.74)	2.22 (1.17-4.22)
Score=3	4.24 (2.68-6.71)	4.62 (2.12-10.53)	4.50 (2.22-9.09)	5.67 (3.08-10.43)	8.76 (3.30-23.25)	4.22 (1.53-11.64)	2.88 (1.36-6.09)	1.03 (0.13-7.91)	5.13 (1.89-13.90)