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. 2012 Mar 30;7(3):e32227. doi: 10.1371/journal.pone.0032227

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Acar et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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and histology samples represented by matrix Y ( Figure 2 ). (a) The 1st column of matrix B corresponding to the in vitro samples mode extracted by a CMTF model can separate cancer (blue-square sign) from normal (light blue-plus sign) tissue samples; (b) Unlike for brain and bone tissues, matrix D corresponding to the histology samples mode extracted using a CMTF model cannot separate cancer samples (red-triangle sign) from healthy (green-star sign) samples; (c) features captured by the common component extracted by CMTF. Cell-graph features identified as influential in the coupled analysis are similar to the features in Figure 5c and 7c with some minor differences.

Inline graphic — and histology samples represented by matrix Y ( Figure 2 ). (a) The 1st column of matrix B corresponding to the in vitro samples mode extracted by a CMTF model can separate cancer (blue-square sign) from normal (light blue-plus sign) tissue samples; (b) Unlike for brain and bone tissues, matrix D corresponding to the histology samples mode extracted using a CMTF model cannot separate cancer samples (red-triangle sign) from healthy (green-star sign) samples; (c) features captured by the common component extracted by CMTF. Cell-graph features identified as influential in the coupled analysis are similar to the features in Figure 5c and 7c with some minor differences.