Figure 10. In vitro vs. histology samples of cancerous tissue (10a Brain, 10b Bone, and 10c Breast samples).

The first two components of SVD analysis explain 72.4%, 65.9%, 66.5% of the variance for each tissue type, respectively. SVD yields a linear separation between in vitro and histology cancerous tissue samples. Two clusters (red and green) are very well separated, with few outliers. This defines and quantifies a structural difference between engineered tissues and the native tissues.